In irreversible binding, very strong covalent bonds are present, which prolongs the effects of drug. MADUNDA EMMANUEL. April 22, 2015 at 7:37 am. The eye itself. Drug Treatment of Glaucoma Anti Asthmatic Drugs Antihistamines Drug Interactions Locally Acting Drugs . 2. Ocular Pharmacology Introduction of drugs used in Eyes Gyanendra Lamichhane, MD LEI, Bhairahawa 2. These include diuretics (water pills), antihistamines, antidepressants, drugs that lower cholesterol, beta-blockers and birth control pills. This is often due to lack of sleep but can be a powerful indicator of drug type. Stimulation of both the systems produces mydriasis and miosis respectively and their paralysis produces opposite effects.1 Mydriatics show their action either by disrupting parasympathetic supply to the eye (atropine) or by over-activating the sympathetic system (phenylephrine). Ophthalmic drugs delivered via systemic routes have proven even less successful due to the blood–aqueous and blood–retinal barriers, and significant side-effects associated with systemic exposure to large doses of drugs. Now customize the name of a clipboard to store your clips. These drugs are used in many life-threatening conditions, including cardiac arrest, shock, asthma attack, or allergic reaction. [Side effects of various drugs acting on the eye]. A symptom of DXM abuse is rapid, involuntary eye movements called nystagmus. 2 3. Cancer Drugs. Sprays have several advantages over eye-drops: a more uniform spread of drug can be achieved. Along with constricting the pupil through the smooth muscle of the iris, pilocarpine will also cause the ciliary muscle to contract. Clipping is a handy way to collect important slides you want to go back to later. Because treatment of eye injuries with these drugs may cause adverse effects on the digestive system, veterinarians often prescribe additional drugs to limit these effects, such as H 2-blockers or proton pump inhibitors. Share. In irreversible binding, very strong covalent bonds are present, which prolongs the effects of drug. They do this either by mimicking the action of the chemical messengers epinephrine and norepinephrine or by stimulating their release. If you continue browsing the site, you agree to the use of cookies on this website. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. General considerations Autonomic Drugs: Drugs that produce their primary therapeutic effect by Mimicking or altering the functions of the ANS. Looks like you’ve clipped this slide to already. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Title: No Slide Title Author: sharris Last modified by: Richard Freeman Created Date: 12/3/1999 1:51:19 AM Document presentation format: On-screen Show (4:3) – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 570094-NTQyZ This the effect is short lived. While direct agonists act by binding directly to muscarinic or nicotinic ACh receptors, indirect agonists prolong the action of endogenous acetylcholine by inhibiting acetylcholinesterase . The binding of drug with receptor may by of two types: Reversible binding; Irreversible binding; In reversible binding, the bond between the drug and receptor is very weak ionic, hydrogen or van der wall. 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Children: Instill one or two drops of 0.5% solution in the eye which may be repeated five to ten minutes later by a second application of 0.5% solution if necessary. precise instillation requiring less manual dexterity than for eye-drop administration and is particularly useful for treating patients with unsteady hand movements. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. When this happens, blood is released into the vessels and ocular capillaries resulting in red eyes. The mechanisms of sympathomimetic drugs can be direct-acting (direct interaction between drug and receptor), such as α-adrenergic agonists, β-adrenergic agonists, and dopaminergic agonists; or indirect-acting (interaction not between drug and receptor), such as MAOIs, COMT inhibitors, release stimulants, and reuptake inhibitors that increase the levels of … tweet; 2 comments . Antiviral agents generally are designed to block viral replication or disable viral proteins. good. October 31, 2014 at 9:01 pm. You can change your ad preferences anytime. Ocular Pharmacology Introduction of drugs used in Eyes Gyanendra Lamichhane, MD LEI, Bhairahawa. 5-fluoro-uracil (5-FU) a cancer chemotherapy drug can lead to scars and closing the tear drainage system, resulting in eye tearing. However, they also cause a … FDA approved prescription drugs for ENT, which are used to cure various conditions relating to ENT (ears, nose, and throat). fahmi. One acetylcholine-like drug that is employed therapeutically is pilocarpine, a selective muscarinic-receptor agonist that is used in eyedrops to constrict the pupil and to decrease the intraocular pressure that is raised in the disease glaucoma. Muscles within the eye control the size of the pupil and the diameter of the ciliary ring. 3. What about eye puffiness? Reply. 14 In vitro … Adrenergic drugs are medications that stimulate certain nerves in your body. 10% to 20% of these injuries result in temporary or permanent vision loss. Cigarettes: Smoking in general, and smoking cigarettes in particular, can lead to cat… Vision Loss and Aging Losing vision is not a normal part of aging. Small Infants: A single instillation of one drop of 0.5% in the eye. If you have relevant content you are willing to share, we would appreciate your contribution. Ophthalmic anesthetics block the transmission of pain signals from the nerve endings of the eye to the brain, numbing the eye. See our Privacy Policy and User Agreement for details. Reply. It is a known retinal toxin, and the effects are irreversible. PowerPoint is the world's most popular presentation software which can let you create professional Eye Care powerpoint presentation easily and in no time. Benzodiazepines: Like alcohol, at recreational doses, these medications can cause altered, double or blurry vision. While direct agonists act by binding directly to muscarinic or nicotinic ACh receptors, indirect agonists prolong the action of endogenous acetylcholine by inhibiting acetylcholinesterase . They are used to reduce painful ciliary spasm, for diagnosing Horners syndrom… As you age, you have a higher risk of developing the following age-related eye diseases and conditions: [Article in German] Thurn G. PIP: The ophthalmological effects of several classes of drugs, including ovulation inhibitors, are discussed. Mechanisms of action. The drug also causes hallucinations. Antiviral drug, any agent used in the treatment of an infectious disease caused by a virus. Drugs acting on the ear, nose or throat This module is under construction. Alcohol: Intoxication can cause double vision or blurry vision. fahmi. Drug Treatment of Glaucoma Anti Asthmatic Drugs Antihistamines Drug Interactions Locally Acting Drugs . of Labor and Industries. Chart and Diagram Slides for PowerPoint - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. Examples of antiviral drugs include agents to combat herpes viruses, influenza viruses, and HIV. The overall health of one's body or lack of health can play a significant role in the health of one's eyes. The most suitable method of administration depends on which area of the eye is the target for the remedy. The time required for drugs to reach their peak concentrations in the eye depends highly on the physicochemical properties of the particular drug. contamination and eye injury due to eye-drop application are avoided Dilated pupils are a sign of an overdose. These drugs are given intravenously or by mouth. It is, however, more commonly mixed into a drink and consumed orally. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Amphetamines: Ecstasy, Molly, MDMA, and similar drugs can cause blurred vision and changes in pupil size. GHB: A depressant sometimes called liquid ecstasy, GHB can be abused by putting the drug in eyes using eye drops. Also see Eye Care for Seniors. Download drug eye index for PC - free download drug eye index for PC/Mac/Windows 7,8,10, Nokia, Blackberry, Xiaomi, Huawei, Oppo… - free download drug eye index Android app, install Android apk app for PC, download free android apk files at choilieng.com Polar Bear, Polar Bear, What Do You Hear? Rho kinase (ROCK) inhibitors target cells in the trabecular meshwork to enhance aqueous humor outflow. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Drugs that cause both pupillary dilatations, as well as cycloplegia (ciliary muscle paralysis), are called as Cycloplegics. Pilocarpine is a direct-acting cholinergic agonist that constricts the pupils of the eyes, thus opening the Schlemm canal to promote drainage of aqueous humor (fluid). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 17 slides: Protect the Eyes from Harm Eye injuries of all types occur at the rate of about 2000/day. This drug is used to treat glaucoma by relieving (intraocular) fluid pressure in the eye and to promote miosis in eye surgery and examinations. This the effect is short lived. Training on the use of eye protection in the workplace from the Washington State Dept. A new class of glaucoma drugs promises to act specifically on the eye’s drainage canals, called the trabecular meshwork, a main outflow and blockage site in glaucoma. The volume of commercial drop dispensers (25–50 μL) generally exceeds the capacity of the conjunctival sac (only 10 μL), so that the major portion of the liquid drains out of the eye and … Share. 1. This administration of drug can be done by instillation of a cream, an ointment, or a liquid drop preparation in the conjunctiva sac. The binding of drug with receptor may by of two types: Reversible binding; Irreversible binding; In reversible binding, the bond between the drug and receptor is very weak ionic, hydrogen or van der wall. L1: Drugs acting on the ANS 1. Ocular Pharmacology 1. 1. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP … “Antihistamines often cause a very significant dry-eye syndrome,” Andreoli says. Heparin, coumadin, anisindione, and other oral anti-coagulants, prescribed to prevent blood clotting can cause hemorrhaging in the eye. When they go to an eye doctor, the eye doctor will see the papilledema,” Dr. Trobe notes. Get an idea about them from this page. If you continue browsing the site, you agree to the use of cookies on this website. Antagonists acting on muscarinic receptors include such drugs as atropine and scopolamine. Drugs Acting on Eye, Respiratory System and Miscellaneous Drugs. Diseases of conjunctiva ppt ophthalmology, ICH pharmacovigilance planning, an efficacy guideline, Antioxidant Vitamin Food Sources PowerPoint, Free radicals and antioxidant vitamins explained pdf, Drugs used in special age groups like children, elderly and preganancy, Optic nerve Diseases By: Sumayya Naseem Optometrist, No public clipboards found for this slide. The uploader spent his/her valuable time to create this Eye … , asthma attack, or allergic reaction agents to combat herpes viruses, viruses... And other oral anti-coagulants, prescribed to prevent blood clotting can cause hemorrhaging the... 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